Author

Y. Reddy

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Open access Sep 2026

Sotatercept Improves Right Heart Mechanics Despite Reduced Myocardial Contractility in Pulmonary Arterial Hypertension - A Prospective Exercise Hemodynamic Study

Background: The right ventricular (RV) response to pressure overload is a crucial determinant of outcomes in pulmonary arterial hypertension(PAH). Sotatercept improves clinical outcomes, but its effects on the RV have been inconsistent. We sought to evaluate the effects of sotatercept on load-independent measures of RV...

Y. Reddy, S. Kazui, W. Miranda et al. · Circulation · 0 citations

Open access Aug 2026

Clinical effectiveness of sodium-glucose cotransporter 2 inhibitors in heart failure with preserved ejection fraction: nationwide cohort study (REFINE-HFpEF)

Abstract Objective To evaluate the clinical effectiveness of sodium glucose cotransporter 2 (SGLT2) inhibitors in reducing the risk of hospital admission for heart failure and mortality in a contemporary nationwide cohort of patients with heart failure with preserved ejection fraction (HFpEF). Design Nationwide cohort...

Padmini Selvaganesan, Mohamad Karnib, Irfan Helmy et al. · BMJ Medicine · 0 citations