Avidity as a marker of protection against hepatitis E during a genotype 1 outbreak in South Sudan
Background: In settings where hepatitis E virus (HEV) is highly endemic, anti-HEV IgG seroprevalence approaches saturation, yet how often disease occurs in previously infected individuals, and how protective natural genotype 1 immunity is, remains unmeasured. IgG concentration cannot answer this as levels rise within d...