Author

Y. She

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Open access Aug 2026

Multi‐Omics Integration Identifies a CDH3‐Associated Malignant Epithelial State and Immunosuppressive Niche to Predict Prognosis in Thymic Epithelial Tumors

ABSTRACT Thymic epithelial tumors (TETs) are rare and heterogeneous malignancies whose aggressive epithelial states and microenvironmental organization remain poorly defined. Here, we integrated single‐cell RNA sequencing, spatial transcriptomics, multiplex immunofluorescence, bulk transcriptomics, functional assays, x...

Yuntao Feng, Jing-Yu Chen, Lang Xia et al. · Advancement of science · 0 citations

Aug 2026

The Multimodal Pretraining Framework CarHE Predicts Spatial Transcriptomics in Tumors from Routine Pathology Images.

Spatial transcriptomic analyses provide spatially resolved gene expression data that can provide insights into complex biological processes. However, current spatial transcriptomics approaches remain financially prohibitive and restricted in resolution, scalability, and gene coverage, limiting broader adoption for larg...

Jiawei Zou, Kai Xiao, Zexi Chen et al. · Cancer Research · 0 citations