2026
Effect of Structure-Guided Single Mutant on Nicotinamide Coenzyme Specificity of Glucose Dehydrogenase from Bacillus Megaterium
A structure-guided rational design to invert the coenzyme specificity of GDH by targeting a single residue within the conserved GXXXGXG motif of the Rossmann fold provides a generalizable framework for engineering cofactor preference in short-chain dehydrogenase/reductase family enzymes.
Y. Shen, Ke-Ju Jing
· International Journal of Fro... · 0 citations