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Author

Y. Shiferaw

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Open access Sep 2026

A structure-based model that describes activation and inactivation of a sodium channel.

While the Hodgkin-Huxley formalism successfully describes sodium channel gating, the molecular origin of its nonlinear voltage dependence remains unclear. We developed a structure-based model of Nav1.4 representing the four voltage-sensing domains, the isoleucine-phenylalanine-methionine (IFM) motif and the S6 gate as...

D'Artagnan Greene, S. Perez, Y. Shiferaw · 0 citations
Oct 2026

When is quantum mechanics required to describe the thermodynamics of the ideal gas?

A persistent conceptual puzzle in statistical mechanics is that the entropy S of a classical ideal gas depends on quantum mechanical quantities such as Planck's constant h and the factor 1/N!, which is commonly attributed to the indistinguishability of quantum particles. We resolve this puzzle by distinguishing entropy...

Y. Shiferaw · 0 citations

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