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Open access Sep 2026

SORDINO: silent, sensitive, specific and artifact-resistant fMRI in awake, behaving mice

Blood-oxygenation-level-dependent (BOLD) functional magnetic resonance imaging (fMRI) has advanced brain mapping across species. This widely used technique, however, faces challenges such as acoustic noise, electromagnetic interference, motion artifacts, magnetic-field inhomogeneity and limitations in sensitivity and s...

Martin J. MacKinnon, Sheng Song, T. Chao et al. · 2 citations
Open access Aug 2026

Excitation-inhibition balance dynamics across brain networks during naturalistic behavior

A dual-color multisite spectrally- resolved fiber photometry platform is developed to simultaneously record genetically defined E and I populations across four cortical regions and identifies transient E-I imbalance as a normal feature of naturalistic behavior, with implications for understanding network dysfunction in...

Nicholas K. Branigan, T. Nghiem, T. Chao et al. · 0 citations

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