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Y. Shin

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Open access Jul 2026

Cryo-EM study of bacteriophage N4 virion RNA polymerase

Cryo-electron microscopy structures of full-length N4 vRNAP in its apo state and in a transcription initiation complex with promoter DNA and initiating nucleotides are reported, revealing how the C-terminal domain regulates polymerase activity through a structural “switch” that locks the enzyme in an inactive state unt...

M. Narwal, Y. Shin, Katsuhiko S. Murakami · 0 citations

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