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Open access Oct 2026

Potential effect of replacing sedentary behavior with physical activity on the risk of atrial fibrillation: results from the UK Biobank and REGARDS study

Background Sedentary behavior (SB) has been associated with cardiovascular disease risk, independent of physical activity (PA) and sleep. However, the effect of replacing SB with PA or sleep on atrial fibrillation (AF) risk remains unclear. Methods We studied 86,096 participants from the United Kingdom Biobank (UKB) an...

L. Li, A. Shah, Y.-A. Ko et al. · 0 citations
Open access Aug 2026

Leukocyte DNA methylation-based signatures for atherosclerotic cardiovascular disease risk prediction in the Million Veteran Program

DNA methylation-based signatures were associated with incident ASCVD and modestly improved risk prediction beyond that of traditional risk factors, and an agnostic probe reliability-based approach was developed.

A. Barad, D. Khodasevich, P. F. Kho et al. · 0 citations

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