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Open access Sep 2026

A Systems Biology Model Linking Peripheral NIMETOX Biomarkers to Multilevel Brain Structural and Functional Alterations Across Major Depression and Schizophrenia

Peripheral lipid and antioxidant-related biomarkers may help contextualize brain abnormalities across psychiatric disorders, but their relationships with brain structure, intrinsic activity, and dimensional symptoms remain incompletely characterized. In this cross-sectional study, 93 adults were recruited: 38 with majo...

H. Wu, C. Yang, Y. He et al. · 0 citations
Open access Sep 2026

Integrating Single-Molecule Variant Phenotyping with Clinical Features Predicts Outcomes in KIF1A-Associated Neurological Disorder

Using KIF1A-associated neurological disorder (KAND) as a model system, single-molecule biophysical phenotyping of 91 pathogenic variants with longitudinal clinical characterization of 343 patients offers a prognostic tool and a stratification strategy for clinical trials.

Lu Rao, Wen-Xing Li, Jessica Waxler et al. · 0 citations

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