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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Y. Zhangsun

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Open access Sep 2026

MFN1 Mediates Doxorubicin-Induced Cytotoxicity through Oxidative Stress-Induced Ferroptosis

Doxorubicin (DOX)-induced cardiotoxicity (DIC) limits clinical application of DOX, and the mechanism is linked to ferroptosis. Mitofusin 1 (MFN1) has been reported to be involved in regulating cell death and mitochondrial dysfunction, yet its role in DIC remains unclear. In an in vitro DIC model using H9c2 cells,...

J. Gao, M. Xue, Y. Zhangsun et al. · 0 citations

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