Residual Glioma Stem Cells and the Post-surgical Microenvironment in Glioblastoma Recurrence: Mechanistic Basis and Therapeutic Potential of Chinese Herbal Medicines and Natural Products
Standard treatment for glioblastoma (GBM) combines maximal safe resection, radiotherapy, and temozolomide, yet recurrence remains common and is usually detected near the resection cavity. Longitudinal single-cell studies, paired primary-recurrent tumor analyses, and resection models indicate that recurrence reflects mo...