Open access
Aug 2026
Zfp217 Regulates Hepatic de Novo Lipogenesis via METTL3-Mediated N6-Methyladenosine Modification of SREBF1.
It is reported that global Zfp217 heterozygous knockout alleviates high-fat diet (HFD)-induced hepatic steatosis in mice, as evidenced by reduced liver weight, decreased hepatic and serum TG and total cholesterol levels, and hepatic lipid deposition.
Shuangshuang Li, Qian-Hui Zeng, Ya-Dan Liu et al.
· The FASEB Journal · 0 citations