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Aug 2026

Neutrophil extracellular traps promote glomerular endothelial injury in IgA nephropathy via the cGAS-STING pathway.

IgA nephropathy (IgAN), a common primary glomerulonephritis, has an incompletely elucidated pathogenesis. Neutrophil extracellular traps (NETs), key components of innate immunity, are known to mediate renal injury in various kidney diseases, yet their role in IgAN remains unclear. In this study, we observed significant...

Xiaotong Li, Qinghua Duan, Yuan Ji et al. · 0 citations
Open access Jul 2026

Hidden genetic diversity in 320 nearly-complete East Asian genome assemblies

East Asian populations, representing over 20% of the global population, remain critically underrepresented in human genomic studies, limiting our understanding of population-stratified genetic variation and its implications for health and disease. Here we present the first phase of the Asian Pan-Genome project (APG), c...

Dongya Wu, Chentao Yang, Quanyu Chen et al. · 2 citations

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