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Open access Sep 2026

HEATR1 deficiency enhanced gastric cancer cell PANoptosis to boost anti-tumor immunity

Despite the promise of immune checkpoint inhibitors (ICIs) for gastric cancer (GC) treatment, limited cytotoxic T cell infiltration remains a major barrier to therapeutic efficacy. This study investigates whether targeting HEAT repeat containing 1 (HEATR1) can induce immunogenic PANoptosis to enhance anti-tumor immunit...

Ya Huang, Qing Xu, Mei Zhu et al. · 0 citations

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