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Author

Ya-Hui Lin

2 papers indexed here

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Open access Sep 2026

Cysteine supplementation reverses immune dysfunction in cancer patients with severe COVID-19

Severe COVID-19 infection in patients with cancer is characterized by a unique pattern of immunologic dysfunction including muted adaptive immune responses. The molecular drivers of immune dysfunction in cancer patients with severe COVID-19 remain unclear, and therapeutic strategies to overcome immune dysfunction in th...

Tiffany Merlinsky, J. Rahman, Wendy Johnson et al. · 0 citations
Open access Sep 2026

Mitochondrial ATP promotes T cell differentiation through chromatin accessibility.

Immune elimination of chronic infection or cancer requires cytotoxic CD8+ T cells that adopt and maintain an effector phenotype. Cytotoxic T cell function is a bioenergetically demanding process. Here, we report the ability of D-α-hydroxybutyrate (DAHB) to act as a signaling molecule that increases mitochondrial ATP pr...

Charles Ng, Tak-Shun Fung, Da-Yi Li et al. · 0 citations

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