Author

Yahui Wan

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Open access Oct 2026

The Effect of the MTHFR C677T Genotype Polymorphism on the Efficacy of Folic Acid Treatment for Hyperhomocysteinemia and Cardiovascular Endothelial Function

ABSTRACT Background Cardiovascular disease remains a major public health burden. This study aimed to investigate the effect of the methylenetetrahydrofolate reductase (MTHFR) C677T genotype on folic acid treatment response and cardiovascular endothelial function in patients with hyperhomocysteinemia (HHcy). Methods We...

Xiao-Hui Dou, Xi-Juan Zhang, Liang Zeng et al. · Chronic Diseases and Transla... · 0 citations

Open access Sep 2026

Association and discriminative value of insulin resistance surrogate markers for aortic stiffness in asymptomatic adults

Insulin resistance surrogate markers, including the triglyceride-glucose (TyG) index, TyG-BMI, and TG/HDL-C ratio, have been associated with aortic stiffness in high-risk populations. Their comparative associations and incremental discrimination in asymptomatic adults remain unclear. We therefore compared these mar...

Zhen-Sen Zhou, Ya-Hui Wan, Yin Cheng et al. · Frontiers in Cardiovascular... · 0 citations

Open access Aug 2026

Development of a Prognostic Model for MACE in Atherosclerosis Based on MTHFR and Serum Markers

This integrated prognostic model demonstrated good internal discrimination and calibration for predicting MACE in patients with AS, and provides a practical risk-stratification framework for identifying individuals at high residual cardiovascular risk.

Xiao-Hui Dou, Xi-Juan Zhang, Liang Zeng et al. · Clinical and applied thrombo... · 0 citations