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Author

Ya-Li Mi

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Open access Sep 2026

Ufd4p-mediated Sum1p clearance ensures proper chromosome organization during cell division.

Chromosome architecture is essential for faithful chromosome segregation and genome stability. However, the mechanisms underlying chromosome organization are not well-characterized. Here, we identify the ubiquitin ligase Ufd4p as a master regulator of chromosome organization. Ufd4p deficiency causes longer chromosome a...

Tai-Cong Tan, Ya-Li Mi, Peng Du et al. · 0 citations
Open access Jul 2026

Dual and opposing roles of the EXD2 exonuclease in the resolution of RNA–DNA hybrids

A mechanistic understanding of the functional roles of EXD2 in cells is provided and it is revealed that overexpressed EXD2 colocalizes with mitochondrial RDHs and, rather than cleavage, prevents them from fast degradation.

Meng Hu, Yinghong Chen, Yanan Li et al. · 0 citations

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