Author

Ya-Ling Li

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Review Open access Jan 2026

TREM2: A Potential Target for the Targeted Therapy of Metabolic Diseases

This review systematically summarize recent advances in understanding the roles of TREM2 in major metabolic diseases, including atherosclerosis, diabetes mellitus and its complications, obesity, and non‐alcoholic steatohepatitis, while highlighting its functional heterogeneity across different diseases contexts.

Ya-Ling Li, Sheng-Quan Liu, C. Chu et al. · Mediators of Inflammation · 0 citations

Review Open access Aug 2026

Mitochondrial damage and post-translational modifications in radiation-induced heart disease: mechanisms and emerging therapeutic targets

It is proposed that persistent disruption of mitochondrial homeostasis represents a central link between early radiation-induced injury and late cardiac remodeling and provides a potential biological explanation for the long latency and progressive nature of RIHD.

Na Zuo, Ya-Ling Li, Jun Yang · Frontiers in Pediatrics · 0 citations