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Author

Ya-Nan Wang

2 papers indexed here

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Open access Oct 2026

SaCas9-Mediated CrtYB Disruption Coupled with Heterologous α-Bisabolol Production in Rhodotorula mucilaginosa JY1105

Rhodotorula mucilaginosa is a promising host for terpene biosynthesis, but its rational engineering remains constrained by limited genome-editing tools. Here, we developed a Staphylococcus aureus Cas9 (SaCas9) workflow in R. mucilaginosa JY1105 for CrtYB disruption and demonstrated heterologous α-bisabolol production....

Wen-Yi Sun, Hao-Yang Liu, Ya-Qi Dong et al. · 0 citations
Sep 2026

Astragalus polysaccharide ameliorates ischemic stroke via modulating the microbiota-gut-brain axis.

Ischemic stroke (IS) remains a major contributor to global disability and mortality. Astragalus polysaccharide (ASP), a naturally active component derived from Astragalus membranaceus, exhibits therapeutic potential against IS. However, their mechanism against IS via the microbiota-gut-brain axis remains unclear. Our s...

Yu Li, Jing Zhang, Shuo Li et al. · 0 citations

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