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Author

Ya-Nan Zhu

2 papers indexed here

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Open access Sep 2026

MxB N-Terminus Adopts a Stable α-Helix to Engage the HIV-1 Capsid Trimer Interface

The HIV-1 capsid, composed of capsid (CA) proteins arranged into a conical surface lattice, serves as a critical platform for host–pathogen interactions. Many host cofactors regulate HIV-1 infection by selectively recognizing the higher-order CA lattice rather than individual monomers or capsomers. Among these, Myxovir...

Ya-Nan Zhu, J. Rey, Juan Shen et al. · 0 citations
Open access Sep 2026

Unveiling structural determinants of peptide recognition by public and private SARS-CoV-2-specific T-cell receptors

Public T cell receptors (TCRs) recurrently emerge across individuals in response to common pathogens, yet the structural and biophysical basis distinguishing public from private clonotypes remains incompletely defined. Here, we combine epitope mapping, single-cell TCR sequencing, and single-particle cryo-electron m...

Caner Akıl, Yan-Chun Peng, Julia McCarthy et al. · 0 citations

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