Grass carp (Ctenopharyngodon Idella) hemorrhagic diseases (GCHD), caused by grass carp reovirus (GCRV), has posed a serious threat to the grass carp aquaculture industry in China. Ubiquitination plays a central role in viral evasion of the host interferon response; therefore, elucidating the mechanisms by which viruses...
Hemorrhagic disease caused by grass carp reovirus (GCRV) poses a severe threat to the grass carp aquaculture industry. Semaphorin 4E-like (Sema4E-like), a teleost-specific signaling molecule, remains poorly understood in immune regulation. In this study, the grass carp Sema4E-like gene was cloned and characterized, rev...
Yu-Huan Shao, Jin-Yan Lei, Ju-Hong Xie et al.· Fish and Shellfish Immunolog...· 0 citations
Double-stranded RNA (dsRNA) reoviruses are primarily sensed by the RIG-I-like receptor (RLRs) signaling pathway. However, whether these viruses can also activate the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway, a central DNA-sensing system, remains poorly understood. Grass carp r...
Zi-Chao Peng, Fang Zhou, Xu-Yang Wang et al.· Cell Communication and Signa...· 0 citations
This research offers significant insights into viral cell invasion and strengthens innate and adaptive immunity, enabling safer, more practical and multilayered control in aquaculture.
Waqar Younas, Mi-Juan Shi, Rong Huang et al.· Reviews in Aquaculture· 0 citations
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