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Open access Oct 2026

DIA Quantitative Proteomic Analysis Reveals Early Proteomic Responses to Honeybee-Derived Melittin in Murine Breast Cancer Cells

Breast cancer remains a major clinical challenge because of its molecular heterogeneity, therapeutic resistance, and disease recurrence. Melittin, the principal bioactive peptide of honeybee venom, exhibits antitumor activity in multiple experimental models; however, its early proteome-wide effects in breast cancer cel...

Jun-Ling Zhu, Wen-Hua Xu, He Zang et al. · 0 citations
Jul 2026

ace-miR-3759-y Orchestrates Honeybee Larval Defense against Fungal Infection through Modulating Dual Targets and Oxidative Stress Response.

Chalkbrood disease, caused by Ascosphaera apis, threatens Apis cerana larvae. However, miRNA-mediated antifungal regulation remains poorly defined. Here, we characterized ace-miR-3759-y in A. apis-challenged A. cerana larvae. Stem-loop RT-PCR and Sanger sequencing confirmed its gut expression. Target prediction identif...

He Zang, Haimei Yue, Xiaoxue Fan et al. · 0 citations

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