Ya-Qiong Zhu

Short-chain fatty acids significantly alleviate cisplatin induced sensory cell damage and hearing loss by maintaining the expression of MUTYH

Cisplatin is a potent, broad-spectrum chemotherapeutic agent widely used against multiple malignancies, yet its clinical utility is substantially restricted by dose-limiting adverse effects dominated by nephrotoxicity and ototoxicity. Although cisplatin-induced ototoxicity has been recognized for decades, the precise...