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Author

Ya-Si Zhang

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Review Sep 2026

Association Between Sinoatrial Node Radiation Dose and New-Onset ECG Abnormalities After Breast Cancer Intensity-Modulated Radiotherapy.

PURPOSE To investigate the association between cardiac conduction system dosimetry, specifically the sinoatrial node (SAN), for new-onset electrocardiogram (ECG) abnormalities in breast cancer (BC) patients undergoing intensity-modulated radiotherapy (IMRT). METHODS We retrospectively reviewed 91 BC patients treated...

Yan-Jun Zhang, Z.-F. Chi, Fei-Fei Wang et al. · 0 citations
Open access Sep 2026

Beyond mean heart dose: differentiated electrocardiographic manifestations and dosimetric mechanisms of cardiac injury in left-sided versus right-sided breast cancer after intensity-modulated radiotherapy

Objective To investigate dosimetric exposure variations to the whole heart and substructures between left- and right-sided breast cancer patients receiving intensity-modulated radiotherapy (IMRT), and to evaluate their relationships with post-radiotherapy (post-RT) electrocardiogram (ECG) alterations. Methods Clinical...

Yan-Jun Zhang, Xiao-Chen Han, Fei-Fei Wang et al. · 0 citations
Open access Aug 2026

Beyond mean heart dose: quantitative impact of sub-structure spatial dosimetrics on subclinical myocardial strain in thoracic radiotherapy

Hyper-acute subclinical strain alterations are highly prevalent immediately after thoracic radiotherapy, with right-sided structures exhibiting enhanced radiosensitivity, and independent sparing of the conduction system and coronary vasculature should be considered in precision radiotherapy, warranting validation in fu...

Yan-Jun Zhang, Xiao-Chen Han, Fei-Fei Wang et al. · 0 citations

Physics in Medicine & Biology

The proposed surface-aware DDIM-RePaint framework provided an accurate and efficient approach for longitudinal CBCT FOV extension, potentially facilitating patient setup and ART planning without extra imaging dose and hardware upgrade.

Jueye Zhang, Qijian Lu, Ya-Si Zhang et al. · 0 citations

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