Yaara Oppenheimer-Shaanan

Genome-wide Identification of Type VI Secretion System Effectors via Machine Learning Uncovers Three New Bacterial Toxins

The type VI secretion system (T6SS) is a molecular harpoon used by 19% of sequenced bacteria to inject toxic proteins into microbial competitors or host cells. Despite its widespread distribution, many T6SS effectors (T6Es) remain unidentified in bacterial genomes. Here, we developed an XGBoost classifier integrating 4...