Author

Ya-Fang Zhang

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Oct 2026

Luteolin as a potential intervention for bleomycin-induced pulmonary fibrosis: targeting the AKT/mTOR/HIF-1α/MMP2 axis.

Pulmonary fibrosis (PF) is a life-threatening interstitial lung disease that endangers human health. Luteolin (LUT), a naturally occurring flavonoid, has exhibited potential effects against pulmonary fibrosis. However, its mechanism of action remains unclear. Here, we investigated the therapeutic effects of LUT against...

Chen-Hao Yao, Yu-Xin Yao, Yan-Zhi Li et al. · Toxicology and Applied Pharm... · 0 citations

Review Open access Jul 2026

Mitochondrial-endoplasmic reticulum interactions in lung diseases.

A deeper understanding of the functional interaction network among mitochondria, the endoplasmic reticulum, and their associated MAMs is expected to provide a robust theoretical foundation and translational insights for elucidating novel molecular mechanisms underlying lung injury and optimizing therapeutic strategies.

Yafang Zhang, Hao Yan, Xi Peng et al. · Cell Death and Disease · 0 citations