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Author

Yan Bi

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Jul 2026

Abstract A029: AI-Driven Network-Based Discovery on TCGA-PAAD Identifies KRAS-Axis Drug-Repurposing Targets for Pancreatic Cancer Interception

AI-guided network analysis of TCGA-PAAD prioritizes biologically coherent KRAS-axis and stromal-inflammatory candidates with clinically available HER2, EGFR, MEK-, BRAF, and KRAS-pathway inhibitors, supporting hypothesis generation for future pancreatic cancer interception studies.

Jian-Fu Li, Yingyun Yang, Michael B. Wallace et al. · 0 citations
Jul 2026

Abstract A046: Pre-diagnostic clinical-trajectory signatures of early-onset pancreatic cancer

The high occult prevalence motivates germline-guided active surveillance for genetically at-risk young adults rather than symptom-driven workup, anchoring next-generation surveillance trial designs in rare and hereditary pancreatic malignancies.

Jian-Fu Li, Yingyun Yang, Wallace Michael et al. · 0 citations

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