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Yanbo Zhang

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Open access Oct 2026

Real-world efficacy and safety of efgartigimod in patients with autoimmune encephalitis: a single-center retrospective analysiss

This study was conducted to evaluate the efficacy and safety of efgartigimod (EFG), a neonatal Fc receptor (FcRn) antagonist, in the treatment of autoimmune encephalitis (AE) under real-world conditions and to provide clinical evidence for treating AE patients who respond poorly to first-line and/or second-line imm...

Zhi-Jiao Song, Lan-Tao Liang, Mei-Ling Zhang et al. · 0 citations
Open access Jul 2026

SLC15A4 Inhibition by NTX-348 Suppresses Endolysosomal Toll-like Receptor Signaling, IRF5 Activation, and Type I Interferon Induction 2249463

In vitro studies show that SLC15A4 inhibition results in the intracellular degradation of the TASL adapter protein and blockade of inflammatory cytokine production in response to TLR7/8/9 agonists, and these results highlight the early progress developing novel, drug-like inhibitors of SLC15A4.

J. McElwee, Ana Antić, A. Basavapathruni et al. · 0 citations

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