Author

Yan Chen

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Open access Sep 2026

CircHIPK3 promotes the progression of B-cell acute lymphoblastic leukemia in children by binding to STAT3

The findings characterize circHIPK3 as a potent oncogenic driver in B-ALL that functions by stabilizing STAT3 via the ubiquitin-proteasome pathway.

Yu Zheng, Yun-Peng Li, Xiu-Li Zhu et al. · Frontiers in Pharmacology · 0 citations

Open access 2026

METTL16 promotes PD-L1 expression and mediates immunosuppression in B-cell lymphomas via m6A methylation.

It is determined that METTL16 promotes BCL progression and immune evasion through epigenetic regulation of the PD-L1/PD-1 pathway and elevated the resistance of BCL cancer to inhibition by anti-PD-L1 therapy.

Yan Chen, Sen Cao, Xiao-Fei Lu et al. · American journal of translat... · 0 citations