Jul 2026
Genomic Disruption of CAMKMT by t(2;11)(p21;q23) Reveals a Glycolytic Reprogramming Mechanism in Acute Myeloid Leukemia.
INTRODUCTION The t(2;11)(p21;q23) translocation without KMT2A rearrangement has been reported in ~16 hematologic neoplasms, but its molecular target(s) remain unknown. We aimed to identify the genes disrupted by this translocation and to clarify its contribution to Acute Myeloid Leukemia (AML) pathogenesis. METHODS W...
Shujun Li, Xiaoshan Yang, Peng Fang et al.
· Current Medicinal Chemistry · 0 citations