Across diverse applications, GeneSPOT resolved tissue structures, integrated paired and unpaired spatial multi-omics data, unveiled the spatial convergence of gene programs during embryonic development, and identified aging-associated spatial reorganization among genes whose expression did not change significantly with...
Qi Zou, Zhi-Kang Wang, Si-Jie Li et al.· bioRxiv· 0 citations
Genetic perturbations can reshape cell populations by altering the relative abundance of specific cell types and states within the profiled population, including increases, decreases and states that become detectable after perturbation. Pooled single-cell screens, such as Perturb-seq, measure such responses at scale. H...
Jia-Peng Chen, Yan Cui, Yan-Jun Shao et al.· bioRxiv· 0 citations
AnchorR is designed to complement automated computer-vision methods by providing reliable tissue-level alignment when border mismatch makes global registration difficult, and operationalizes an expert-in-the-loop approach and makes feature-based multimodal registration accessible without specialized computer-vision exp...
Caitlin A Morris, William C. Bastian, Yan Cui et al.· bioRxiv· 1 citation
Spatial Hi-C-RNA provides a broadly applicable framework for investigating genome structure–function relationships in development and disease within native tissue environments within native tissue environments.
Pengfei Guo, Yan Cui, Jin-Can He et al.· Cell· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
