Author

Yan-Fei Liu

3 papers indexed here

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Oct 2026

Self-assembled ferric-shikonin-quercetin (FSQ) nanoparticles co-delivering R848 enable lactate reduction, ICD induction, and immune modulation in vitro.

To overcome inadequate tumor immunogenicity and the immunosuppressive tumor microenvironment, a self-assembled nanomedicine (R848@FSQ) is developed by coordinating the chemotherapeutic drugs shikonin (SHK) and quercetin (Qu) with Fe3 + to form a metal-phenolic network (MPN), and is simultaneously loaded with the immune...

Xing-Xing Peng, Qi-Wen Chen, Jing Chang et al. · Colloids and Surfaces B: Bio... · 0 citations

Sep 2026

Inhalable mucus-penetrating and senescence-targeted nanoliposomes reverse senescence to overcome chemoresistance for enhanced lung cancer therapy.

Lung cancer therapy is severely hindered by the pulmonary mucus barrier and chemotherapy resistance driven by therapy-induced senescence (TIS) following DNA-damaging agents. Herein, we report an inhalable, mucus-penetrating nanoliposomes (DR@DPPC-Apt) engineered by incorporating an L1 cell adhesion molecule (L1CAM)-tar...

Yun-Qi Man, Yan-Fei Liu, Yong-Bo Liu et al. · Biomaterials · 0 citations

Review Sep 2026

Multidimensional Regulatory Network of Cellular Senescence: From Mechanisms to Theranostics.

This review systematically maps the molecular architecture of the senescent-cell heterogeneity, off-target toxicity, and the lack of standardized biomarkers, and provides a framework for developing precision strategies to detect, modulate, or eliminate senescent cells in a context-appropriate manner.

Ze-Xiang Lv, Yan-Fei Liu, Yong-Bo Liu et al. · ACS Biomaterials Science & E... · 0 citations