Osteoporosis, featured by imbalanced bone remodeling, faces clinical challenges including microenvironment dysregulation, insufficient mineralization, and poor material fixation. Inspired by natural bone regeneration-where ossification centers and surrounding soft tissues orchestrate mineralization and tissue integrati...
The locomotor system organoids, which recapitulate bones, cartilage, tendons, muscles, and associated neurovascular-like structures, possess complex architecture and biomechanical properties. Traditional two-dimensional (2D) cell models struggle to effectively mimic their physiological functions. Organoid technology,...
Rui Wang, Ye Tian, Geng-Hao Wang et al.· Regenerative Biomaterials· 0 citations
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