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Open access Aug 2026

Transmetallic biomimetic Hydrogel implants restore osteogenesis-angiogenesis coupling via Fe/Co ionic microenvironment remodeling for enhancing osteoporotic fracture healing

The regeneration of osteoporotic bone fractures remains a significant clinical challenge, primarily due to the iron overload-induced functional impairment in osteoporosis-angiogenesis coupling. Here, we developed a transmetallic biomimetic hydrogel implant (TBH) to address this issue. The TBH was fabricated by crosslin...

Hao Wei, Xin-Qiang Hu, Maohua Chen et al. · 0 citations
Review Open access Aug 2026

Nanozyme-Mediated Cellular and Microenvironmental Metabolic Reprogramming for Boosting Cancer Immunotherapy.

The potential of nanozymes to directly modulate immunometabolic pathways to empower immunotherapeutic efficacy is reviewed and the synergy of nanozymes with established immunotherapeutics such as immune checkpoint inhibitors, adoptive cell therapies, and cancer vaccines is explored.

Bi-Li Zhang, Meng-Huan Li, Yan Hu et al. · 0 citations

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