Yan-Hu Huang

Dietary soy fiber limits Salmonella infection by disrupting the self-reinforcing loop between pathogen virulence and host inflammation.

The global threat of Salmonella Enteritidis (S. Enteritidis) is exacerbated by its ability to exploit host inflammation for colonization. Here, we find that dietary soy fiber (SF) confers colonization resistance by suppressing S. Enteritidis virulence and host inflammatory amplification. We identify harmaline (HAL), de...