PD-L1 in Ovarian Cancer: Immune Evasion, Tumor-Intrinsic Signaling, and Chemoresistance.
Epithelial ovarian cancer remains a lethal malignancy, primarily due to late-stage presentation and the frequent development of platinum resistance. While immune checkpoint blockade (ICB) targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) axis has revolutionized oncology, its success...