Author

Yan-Lin Zhao

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Review Open access Aug 2026

TBpop: an open-access portal integrating genomic variation, population genetic statistics, phylogeny, pangenome composition, and strain metadata of Mycobacterium tuberculosis isolates from a population-representative survey in China

TBpop provides an integrated platform for exploring genome plasticity, signatures of positive selection, and conservation patterns of functionally important genes in MTB, and three interactive explorer modules: the Population Explorer, the Statistics Explorer, and the Variation Explorer.

Yang Zhou, Fei Huang, Yan-Lin Zhao · bioRxiv · 0 citations

Review Open access Aug 2026

Algorithmic Determinants of Performance Heterogeneity in Whole-Genome Sequencing-Based Prediction of Drug Resistance in Mycobacterium tuberculosis: A Systematic Review and Meta-Analysis

WGS-based bioinformatic tools provide highly specific and generally sensitive predictions of Mycobacterium tuberculosis resistance for first-line drugs across diverse clinical settings and should use prospective head-to-head evaluations on shared, geographically diverse isolate collections, alongside continued improvem...

Baozhen Peng, Yang Zhou, Xiang-Chen Li et al. · Microorganisms · 0 citations