Anhedonia, a prominent symptom of major depressive disorder (MDD), severely impairs patients’ quality of life and is challenging to treat. Although esketamine has shown potential in treating anhedonia in adult treatment-resistant MDD, its effects on adolescents remain under-explored.
In this study, a prosp...
Qian-Qian Wu, Wei-Cheng Li, Zhan-Jie Luo et al.· BMC Psychiatry· 0 citations
Efficient auditory attention requires prioritizing target over nontarget information. Although attentional deficits are a core feature of attention-deficit/hyperactivity disorder (ADHD), the neural mechanisms underlying auditory prioritization during cross-modal attention remain unclear. We examined neural differentiat...
The FCND-guided target framework provides a personalized, mechanism-informed strategy for precision neuromodulation in MDD and is statistically consistent with the hypothesis that distance influences improvement through Z-score normalization in the active group, with a directionally consistent trend in the iTBS dataset...
Zhan-Jie Luo, Wei-Cheng Li, Guanxi Liu et al.· Biological Psychiatry· 0 citations
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