Author

Yan-Long Wang

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Open access Aug 2026

Disruption of the AR/ZNF217/PROM2 axis sensitizes prostate cancer to ferroptosis and enzalutamide therapy

These findings identify AR/ZNF217/PROM2 signaling as a central determinant of ferroptotic vulnerability in prostate cancer and suggest that targeting this pathway may enhance sensitivity to AR inhibition, providing a molecular rationale for combination therapy in castration-resistant prostate cancer.

Wenjun Hao, Peng Liang, Wanglong Zheng et al. · Oncogenesis · 0 citations

Case report Open access Jul 2026

Compound heterozygous variants in PATL2 cause oocyte germinal vesicle arrest associated with primary infertility: a case report and literature review

GV arrest caused by PATL2 defects cannot be overcome by conventional or optimized IVF protocols even with individualized COH, and Donor-oocyte IVF remains the ultimate effective strategy for pregnancy in such patients.

Xiaoxia Song, Lei Yan, Yiwen Zhang et al. · Frontiers in Medicine · 0 citations