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Author

Yan-Qing Wu

2 papers indexed here

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Oct 2026

Repurposing the gastroprotective agent geranylgeranylacetone for atherosclerosis: a novel role of the HSP22-Nrf2-mitochondrial axis.

Mitochondrial dysfunction is a pivotal driver of vascular endothelial injury and atherogenesis. This study aimed to evaluate the therapeutic potential of geranylgeranylacetone (GGA), a clinically established gastroprotective agent, in atherosclerosis and to explore the underlying molecular mechanisms. Apolipoprotein E-...

Meng Li, Yi Chen, Zhi-Jian Wu et al. · 0 citations
Oct 2026

Stepwise dual antiplatelet therapy de-escalation versus standard therapy for 12 months in patients with bifurcation lesions undergoing drug-coated balloon angioplasty: Insights from the REC-CAGEFREE II trial.

BACKGROUND The optimal antiplatelet strategy for patients with acute coronary syndrome (ACS) and bifurcation lesions undergoing drug-coated balloon (DCB) angioplasty remains unclear. METHODS This was a prespecified subgroup analysis of the REC-CAGEFREE II trial, which randomized 1948 ACS patients undergoing DCB-only...

Yong-Meng Yan, Qiong Wang, Yi Liu et al. · 0 citations

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