KDM1A promotes colorectal cancer growth by regulating the HIF-1α/PDK4-mediated glycolysis.
This study elucidated the mechanism by which lysine-specific demethylase 1 A (KDM1A) promotes colorectal cancer (CRC) progression. We characterized KDM1A expression in CRC cells and tissues and examined its effects on malignant phenotypes, including proliferation, migration, invasion, and glycolysis. Mechanistically, w...