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Twenty-year persistence of SARS-CoV-1 immune imprinting shapes antibody responses to SARS-CoV-2 infection.
Study of individuals sequentially infected with SARS-CoV-1 and SARS-CoV-2 over two decades and found durable imprinting of antibody responses following SARS-2 BF.7 breakthrough infection defines the remarkable longevity and molecular basis of antibody imprinting and provides insights for pan-sarbecovirus vaccine design...
Patient-reported outcomes in Chinese patients with AQP4-IgG–positive neuromyelitis optica spectrum disorder on inebilizumab therapy: a cross-sectional study
In this cross-sectional survey, Chinese patients with AQP4-IgG–positive NMOSD receiving inebilizumab reported high satisfaction, perceived multidimensional benefit, and strong treatment continuation willingness, providing exploratory patient-reported evidence regarding the acceptability of inebilizumab in routine pract...