Author

Yan-yan Sun

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Oct 2026

Fungal Phosphatase-Dependent Induction of Host Cell Pyroptosis by Candidalysin

It is shown that candidalysin, the cytolytic peptide toxin of Candida albicans, induces cell type-specific pyroptosis in epithelial cells and macrophages through GSDME and GSDMD activation, respectively, and that PHO100-mediated phosphate regulation contributed to fungal growth and hyphal development under phosphate li...

Yue-Mei Hong, Xiu-Li Wang, Lu Wang et al. · ACS Infectious Diseases · 0 citations

Jul 2026

Integrative analysis of transcriptomics and metabolomics reveals mitochondria function genes and associated metabolite pathways in endometritis.

This study attempted to investigate the pathogenic mechanism of endometritis and discover potential biomarkers for diagnosing and treating endometritis, finding hub genes (ALDH3A2 and ACSS3) play critical roles in the pathogenesis of endometritis by interacting with different metabolites.

Anran Xu, Yanyan Chen, Yanjun Zheng et al. · Gene · 0 citations