Yan-Yu Xu

From physiological homeostasis to pathological injury: Cell-specific functions, imbalance mechanisms, and disease biomarker value of brain lipid droplets.

Lipid droplets (LDs) are versatile cellular structures that consist of a core made of neutral lipids, surrounded by a monolayer of phospholipid membrane. Beyond energy storage, LDs serve as critical immunometabolic platforms that govern microglial activation states and neuroinflammatory cascades. Their formation and fu...