Author

Yan Zheng

2 papers indexed here

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Aug 2026

A temporally coordinated MXene@PDA hydrogel sequentially orchestrates hemostasis, inflammation resolution, and angiogenesis for wound repair.

Uncontrolled hemorrhage and oxidative stress-driven inflammation following acute trauma remain major clinical challenges. Here, we report an ultrafast self-gelling biomimetic hydrogel (PSMP) that integrates an MXene@polydopamine (MXene@PDA) heterojunction nanozyme into a dynamic polyvinyl alcohol/silk fibroin matrix. P...

Chao Liu, Lu Tan, Yu Zhai et al. · Biomaterials · 0 citations

Open access Sep 2026

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

ABSTRACT Annulus fibrosus (AF) rupture is a key structural event in intervertebral disc degeneration, but effective repair is hindered by the acidic, hypoxic and oxidative microenvironment of the avascular disc. Single‐cell transcriptomic reanalysis and clinical AF specimens identified ferroptosis‐associated redox imba...

Lu Tan, Yan Zheng, Yue Lan et al. · Advancement of science · 0 citations