Integrated multi-omics analysis reveals the co-adaptive mechanisms between ruminal microbiota and host epithelium in water buffaloes under chronic heat stress.
The adaptive response of water buffaloes to chronic heat stress is primarily driven by the functional plasticity of the ruminal microbiome, which maintains energy supply and metabolic homeostasis to some extent by altering carbon and nitrogen metabolic fluxes; meanwhile, transcriptional regulation in the host rumen epi...