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Yan-Zhou Li

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Open access Oct 2026

SIRT1–Redox Crosstalk in Aging: Adaptive Capacity and Cellular State Transitions

Aging gradually reduces the ability of cells to maintain and restore homeostasis under metabolic and oxidative stress. Sirtuin 1 (SIRT1) is an NAD+-dependent deacetylase that regulates metabolism, mitochondrial function, inflammatory signaling, and cellular stress responses. Its activity depends on NAD+ availability, r...

Meng-Ting Yan, Lin-Rui Hua, Yun-Ju He et al. · 0 citations

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