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Yanan Huang

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Jul 2026

A Glimpse into the Initial Microsecond of Biomolecular Condensation.

Investigating the first microsecond of peptide condensation through temperature jump infrared spectroscopy and molecular dynamics simulations reveals that hydrogen bonding could enable hydrophobic disordered proteins to adopt preorganized conformations in response to environmental stimuli and serve as a key factor in mediating the assembly kinetics in complex cellular environments.

Longchen Zhu, Guohong Liao, Yumeng Zhang et al. · 0 citations