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Yanbing Xu

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Review Open access Jul 2026

How to Mitigate CRISPR-Cas9 Off-Target Effects: Evaluation of Current Detection, Prediction, and Mitigation Strategies

This review provides a thorough overview of the current state of knowledge on off-target causes, detection and prediction methods, and mitigation strategies for CRISPR-Cas9 applications, and integrates these dimensions to provide a clear framework for controlling when, where and how CRISPR-Cas9-mediated alterations occur.

Yanbing Xu · 0 citations
Open access Aug 2026

Targeting TWEAK to enhance mitochondrial biogenesis and attenuate age-related muscle mass loss

Findings indicate that TWEAK suppression may represent a promising strategy for preserving muscle mass and metabolic homeostasis during aging, though its capacity to fully restore functional capacity requires further investigation.

Zhuoya Maimaitiwusiman, Saiyare Xuekelati, An-Ni Wang et al. · 0 citations