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Open access Aug 2026

Gut microbiota-derived acetate mitigates Escherichia fergusonii-induced gut dysbiosis exacerbating Klebsiella pneumoniae pulmonary infection in mice

Escherichia fergusonii is an emerging food-borne opportunistic pathogen that disrupts gut homeostasis and exacerbates the severity of other organ diseases. However, the effects of gut colonization by E. fergusonii on the gut-lung axis remain unclear. Here we show that the abundance of Escherichia increases in microbiot...

Yu-Yuan Li, Jing Yu, Qi Li et al. · 0 citations
Open access Aug 2026

Interpretable machine learning identifies immune-inflammatory and immunothrombotic biomarkers for myocardial injury and mortality risk stratification in severe pneumonia with diverse infectious etiologies

Background Severe pneumonia is frequently associated with dysregulated immune-inflammatory responses and immunothrombotic activation, contributing to myocardial injury and adverse clinical outcomes. Early identification of patients at high risk for myocardial injury and mortality across varied infectious etiologies rem...

Yi-Cheng Wang, Feng Li, Tian-Qiang Yan et al. · 0 citations

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